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Regulation of type II collagen, matrix metalloproteinase-13 and cell proliferation by interleukin-1β is mediated by curcumin via inhibition of NF-κB signaling in rat chondrocytes
Curcumin possesses strong anti-inflammatory, anti-rheumatoid and anti-oxidative activities, and has the potential to inhibit nuclear factor-κB (NF-κB) signaling. Cartilage damage in osteoarthritis (OA) is largely mediated by interleukin-1β (IL-1β) via activation of various transcription factors, inc...
Autores principales: | Wang, Jian, Ma, Jie, Gu, Jian-Hua, Wang, Fu-Yong, Shang, Xiu-Shuai, Tao, Hai-Rong, Wang, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562050/ https://www.ncbi.nlm.nih.gov/pubmed/28627596 http://dx.doi.org/10.3892/mmr.2017.6771 |
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