HMGB1 regulates P-glycoprotein expression in status epilepticus rat brains via the RAGE/NF-κB signaling pathway

Overexpression of P-glycoprotein (P-gp) in the brain is an important mechanism involved in drug-resistant epilepsy (DRE). High-mobility group box 1 (HMGB1), an inflammatory cytokine, significantly increases following seizures and may be involved in upregulation of P-gp. However, the underlying mecha...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Yuan, Yu, Nian, Chen, Yan, Zhang, Kang, Ma, Hai-Yan, Di, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562060/
https://www.ncbi.nlm.nih.gov/pubmed/28627626
http://dx.doi.org/10.3892/mmr.2017.6772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562060/
https://www.ncbi.nlm.nih.gov/pubmed/28627626
http://dx.doi.org/10.3892/mmr.2017.6772

Ejemplares similares