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HMGB1 regulates P-glycoprotein expression in status epilepticus rat brains via the RAGE/NF-κB signaling pathway

Overexpression of P-glycoprotein (P-gp) in the brain is an important mechanism involved in drug-resistant epilepsy (DRE). High-mobility group box 1 (HMGB1), an inflammatory cytokine, significantly increases following seizures and may be involved in upregulation of P-gp. However, the underlying mecha...

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Detalles Bibliográficos
Autores principales:	Xie, Yuan, Yu, Nian, Chen, Yan, Zhang, Kang, Ma, Hai-Yan, Di, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562060/ https://www.ncbi.nlm.nih.gov/pubmed/28627626 http://dx.doi.org/10.3892/mmr.2017.6772

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