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Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells

Immunotherapy is expected to be promising as a next generation cancer therapy. Immunoreceptors are often activated constitutively in cancer cells, however, such levels of ligand expression are not effectively recognized by the native immune system due to tumor microenvironmental adaptation. Studies...

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Detalles Bibliográficos
Autores principales: Nakajima, Nakako Izumi, Niimi, Atsuko, Isono, Mayu, Oike, Takahiro, Sato, Hiro, Nakano, Takashi, Shibata, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562072/
https://www.ncbi.nlm.nih.gov/pubmed/28677817
http://dx.doi.org/10.3892/or.2017.5773