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Resveratrol inhibits hypoxia-induced proliferation and migration of pulmonary artery vascular smooth muscle cells by inhibiting the phosphoinositide 3-kinase/protein kinase B signaling pathway

Hypoxia is a risk factor for severe chronic obstructive pulmonary disease, which aggravates the disease and may cause mortality by inducing hypoxic pulmonary hypertension (HPH). Proliferation and migration of pulmonary artery smooth muscle cells (PASMCs) may mediate this effect. Resveratrol is a phe...

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Detalles Bibliográficos
Autores principales: Guan, Zhanjiang, Shen, Li, Liang, Huan, Yu, Haitao, Hei, Bingchang, Meng, Xianguo, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562090/
https://www.ncbi.nlm.nih.gov/pubmed/28656233
http://dx.doi.org/10.3892/mmr.2017.6814