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Ketamine Modulates Hippocampal Neurochemistry and Functional Connectivity – A Combined Magnetic Resonance Spectroscopy and Resting State fMRI Study in Healthy Volunteers

A growing body of evidence suggests glutamate excess in schizophrenia and that N-methyl-d-aspartate receptor (NMDAR) hypofunction on γ-aminobutyric acid (GABA) interneurons disinhibiting pyramidal cells may be relevant to this hyperglutamatergic state. To better understand how NMDAR hypofunction aff...

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Detalles Bibliográficos
Autores principales: Kraguljac, Nina V., Frölich, Michael A., Tran, Steve, White, David M., Nichols, Nona, Barton-McArdle, Alexander, Reid, Meredith A., Bolding, Mark S., Lahti, Adrienne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562151/
https://www.ncbi.nlm.nih.gov/pubmed/27480494
http://dx.doi.org/10.1038/mp.2016.122