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C-X-C Motif Chemokine 10 Impairs Autophagy and Autolysosome Formation in Non-alcoholic Steatohepatitis

C-X-C motif chemokine 10 (CXCL10) is a crucial pro-inflammatory factor in chronic hepatitis. Autophagy dysregulation is known to contribute to hepatic inflammatory injury. Hence, we investigated the regulatory effect of CXCL10 on the autophagosome-lysosome system during non-alcoholic fatty liver dis...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang, Wu, William KK, Xu, Weiqi, Man, Kwan, Wang, Xiaojuan, Han, Juqiang, Leung, Wing Yan, Wu, Ruonan, Liu, Ken, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562218/
https://www.ncbi.nlm.nih.gov/pubmed/28824718
http://dx.doi.org/10.7150/thno.19068