Cargando…

Persistent infection due to a small-colony variant of Burkholderia pseudomallei leads to PD-1 upregulation on circulating immune cells and mononuclear infiltration in viscera of experimental BALB/c mice

BACKGROUND: Melioidosis is a neglected tropical disease endemic across South East Asia and Northern Australia. The etiological agent, Burkholderia pseudomallei (B.pseudomallei), is a Gram-negative, rod-shaped, motile bacterium residing in the soil and muddy water across endemic regions of the tropic...

Descripción completa

Detalles Bibliográficos
Autores principales: See, Jia-Xiang, Chandramathi, Samudi, Abdulla, Mahmood Ameen, Vadivelu, Jamuna, Shankar, Esaki M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562302/
https://www.ncbi.nlm.nih.gov/pubmed/28820897
http://dx.doi.org/10.1371/journal.pntd.0005702