Impact of novel palmitoylated prolactin-releasing peptide analogs on metabolic changes in mice with diet-induced obesity

Analogs of anorexigenic neuropeptides, such as prolactin-releasing peptide (PrRP), have a potential as new anti-obesity drugs. In our previous study, palmitic acid attached to the N-terminus of PrRP enabled its central anorexigenic effects after peripheral administration. In this study, two linkers,...

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Detalles Bibliográficos
Autores principales: Pražienková, Veronika, Holubová, Martina, Pelantová, Helena, Bugáňová, Martina, Pirník, Zdenko, Mikulášková, Barbora, Popelová, Andrea, Blechová, Miroslava, Haluzík, Martin, Železná, Blanka, Kuzma, Marek, Kuneš, Jaroslav, Maletínská, Lenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562305/
https://www.ncbi.nlm.nih.gov/pubmed/28820912
http://dx.doi.org/10.1371/journal.pone.0183449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562305/
https://www.ncbi.nlm.nih.gov/pubmed/28820912
http://dx.doi.org/10.1371/journal.pone.0183449

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