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Maternal autoimmune antibodies alter the dendritic arbor and spine numbers in the infragranular layers of the cortex

An association between maternal IgG antibodies reactive against proteins in fetal brain and an outcome of autism in the child has been identified. Using a mouse model of prenatal intraventricular administration of autism-specific maternal IgG, we demonstrated that these antibodies produce behavioral...

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Detalles Bibliográficos
Autores principales: Ariza, Jeanelle, Hurtado, Jesus, Rogers, Haille, Ikeda, Raymond, Dill, Michael, Steward, Craig, Creary, Donnay, Van de Water, Judy, Martínez-Cerdeño, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562324/
https://www.ncbi.nlm.nih.gov/pubmed/28820892
http://dx.doi.org/10.1371/journal.pone.0183443