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Maternal autoimmune antibodies alter the dendritic arbor and spine numbers in the infragranular layers of the cortex
An association between maternal IgG antibodies reactive against proteins in fetal brain and an outcome of autism in the child has been identified. Using a mouse model of prenatal intraventricular administration of autism-specific maternal IgG, we demonstrated that these antibodies produce behavioral...
Autores principales: | Ariza, Jeanelle, Hurtado, Jesus, Rogers, Haille, Ikeda, Raymond, Dill, Michael, Steward, Craig, Creary, Donnay, Van de Water, Judy, Martínez-Cerdeño, Verónica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562324/ https://www.ncbi.nlm.nih.gov/pubmed/28820892 http://dx.doi.org/10.1371/journal.pone.0183443 |
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