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Role of Melatonin in Reducing Amphetamine-Induced Degeneration in Substantia Nigra of Rats via Calpain and Calpastatin Interaction

Excessive intracellular calcium levels induce calpain activation, thereby triggering the cell death cascade. Several lines of evidence have demonstrated the neuroprotective role of the overexpression of calpain inhibitor, calpastatin. In this study, amphetamine-induced degeneration in the substantia...

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Detalles Bibliográficos
Autores principales: Chetsawang, Jirapa, Mukda, Sujira, Srimokra, Rachneekorn, Govitrapong, Piyarat, Chetsawang, Banthit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562346/
https://www.ncbi.nlm.nih.gov/pubmed/29104429
http://dx.doi.org/10.1177/1179069517719237