In silico analysis of glycinamide ribonucleotide transformylase inhibition by PY873, PY899 and DIA

In humans, purine de novo synthesis pathway consists of multi-functional enzymes. Nucleotide metabolism enzymes are potential drug targets for treating cancer and autoimmune diseases. Glycinamide ribonucleotide transformylase (GART) is one of the most important trifunctional enzymes involved in puri...

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Detalles Bibliográficos
Autores principales: Batool, Sidra, Nawaz, Muhammad Sulaman, Mushtaq, Gohar, Parvaiz, Fahed, Kamal, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562383/
https://www.ncbi.nlm.nih.gov/pubmed/28855807
http://dx.doi.org/10.1016/j.sjbs.2014.11.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562383/
https://www.ncbi.nlm.nih.gov/pubmed/28855807
http://dx.doi.org/10.1016/j.sjbs.2014.11.008

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