Cargando…
In silico analysis of glycinamide ribonucleotide transformylase inhibition by PY873, PY899 and DIA
In humans, purine de novo synthesis pathway consists of multi-functional enzymes. Nucleotide metabolism enzymes are potential drug targets for treating cancer and autoimmune diseases. Glycinamide ribonucleotide transformylase (GART) is one of the most important trifunctional enzymes involved in puri...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562383/ https://www.ncbi.nlm.nih.gov/pubmed/28855807 http://dx.doi.org/10.1016/j.sjbs.2014.11.008 |