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Murine Myocardial Transcriptome Analysis Reveals a Critical Role of COPS8 in the Gene Expression of Cullin-RING Ligase Substrate Receptors and Redox and Vesicle Trafficking Pathways

Background: The COP9 signalosome (CSN) consisting of 8 unique protein subunits (COPS1 through COPS8) serves as the cullin deneddylase, regulating the catalytic dynamics of cullin RING ligases (CRLs), the largest family of ubiquitin ligases Background: The COP9 signalosome (CSN) consisting of 8 uniqu...

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Detalles Bibliográficos
Autores principales: Abdullah, Ammara, Eyster, Kathleen M., Bjordahl, Travis, Xiao, Peng, Zeng, Erliang, Wang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562692/
https://www.ncbi.nlm.nih.gov/pubmed/28861005
http://dx.doi.org/10.3389/fphys.2017.00594