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IRS4, a novel modulator of BMP/Smad and Akt signalling during early muscle differentiation

Elaborate regulatory networks of the Bone Morphogenetic Protein (BMP) pathways ensure precise signalling outcome during cell differentiation and tissue homeostasis. Here, we identified IRS4 as a novel regulator of BMP signal transduction and provide molecular insights how it integrates into the sign...

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Detalles Bibliográficos
Autores principales: Dörpholz, Gina, Murgai, Arunima, Jatzlau, Jerome, Horbelt, Daniel, Belverdi, Mohammad Poorgholi, Heroven, Christina, Schreiber, Isabelle, Wendel, Gisela, Ruschke, Karen, Stricker, Sigmar, Knaus, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562708/
https://www.ncbi.nlm.nih.gov/pubmed/28821740
http://dx.doi.org/10.1038/s41598-017-08676-6