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Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4

Ebola virus (EBOV), a member of the Filoviridae family, causes the most severe form of viral hemorrhagic fever. Although no FDA licensed vaccine or treatment against Ebola virus disease (EVD) is currently available, Ebola virus glycoprotein (GP) is the major antigen used in all candidate Ebola vacci...

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Detalles Bibliográficos
Autores principales: Lai, Chih-Yun, Strange, Daniel P., Wong, Teri Ann S., Lehrer, Axel T., Verma, Saguna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562721/
https://www.ncbi.nlm.nih.gov/pubmed/28861075
http://dx.doi.org/10.3389/fmicb.2017.01571