N-glycosylation Triggers a Dual Selection Pressure in Eukaryotic Secretory Proteins

Nearly one third of the eukaryotic proteome traverses the secretory pathway and most of these proteins are N-glycosylated in the lumen of the endoplasmic reticulum. N-glycans fulfill multiple structural and biological functions, and are crucial for productive folding of many glycoproteins. N-glycosy...

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Detalles Bibliográficos
Autores principales: Medus, Máximo Lopez, Gomez, Gabriela E., Zacchi, Lucía F., Couto, Paula M., Labriola, Carlos A., Labanda, María S., Bielsa, Rodrigo Corti, Clérico, Eugenia M., Schulz, Benjamin L., Caramelo, Julio J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562741/
https://www.ncbi.nlm.nih.gov/pubmed/28821844
http://dx.doi.org/10.1038/s41598-017-09173-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562741/
https://www.ncbi.nlm.nih.gov/pubmed/28821844
http://dx.doi.org/10.1038/s41598-017-09173-6

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