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Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis
For faithful chromosome segregation, the formation of stable kinetochore–microtubule attachment and its monitoring by the spindle assembly checkpoint (SAC) are coordinately regulated by mechanisms that are currently ill-defined. Here, we show that polo-like kinase 1 (Plk1), which is instrumental in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562746/ https://www.ncbi.nlm.nih.gov/pubmed/28821799 http://dx.doi.org/10.1038/s41598-017-09114-3 |