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Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform
Many drugs have progressed through preclinical and clinical trials and have been available – for years in some cases – before being recalled by the FDA for unanticipated toxicity in humans. One reason for such poor translation from drug candidate to successful use is a lack of model systems that acc...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562747/ https://www.ncbi.nlm.nih.gov/pubmed/28821762 http://dx.doi.org/10.1038/s41598-017-08879-x |