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Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform

Many drugs have progressed through preclinical and clinical trials and have been available – for years in some cases – before being recalled by the FDA for unanticipated toxicity in humans. One reason for such poor translation from drug candidate to successful use is a lack of model systems that acc...

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Detalles Bibliográficos
Autores principales:	Skardal, Aleksander, Murphy, Sean V., Devarasetty, Mahesh, Mead, Ivy, Kang, Hyun-Wook, Seol, Young-Joon, Shrike Zhang, Yu, Shin, Su-Ryon, Zhao, Liang, Aleman, Julio, Hall, Adam R., Shupe, Thomas D., Kleensang, Andre, Dokmeci, Mehmet R., Jin Lee, Sang, Jackson, John D., Yoo, James J., Hartung, Thomas, Khademhosseini, Ali, Soker, Shay, Bishop, Colin E., Atala, Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562747/ https://www.ncbi.nlm.nih.gov/pubmed/28821762 http://dx.doi.org/10.1038/s41598-017-08879-x

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