Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes

Many behaviors of cancer, such as progression, metastasis and drug resistance etc., cannot be fully understood by genetic mutations or intracellular signaling alone. Instead, they are emergent properties of the cell community which forms a tumor. Studies of tumor heterogeneity reveal that many cance...

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Detalles Bibliográficos
Autores principales: Zhou, Joseph X., Taramelli, Roberto, Pedrini, Edoardo, Knijnenburg, Theo, Huang, Sui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562796/
https://www.ncbi.nlm.nih.gov/pubmed/28821810
http://dx.doi.org/10.1038/s41598-017-09307-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562796/
https://www.ncbi.nlm.nih.gov/pubmed/28821810
http://dx.doi.org/10.1038/s41598-017-09307-w

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