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Identification of the N-terminal transmembrane domain of StarD7 and its importance for mitochondrial outer membrane localization and phosphatidylcholine transfer

StarD7 facilitates phosphatidylcholine (PC) transfer to mitochondria, and is essential for mitochondrial homeostasis. However, the molecular mechanism for PC transfer by protein remains poorly understood. Herein, we describe a putative novel transmembrane (TM) domain C-terminal to the mitochondria-t...

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Detalles Bibliográficos
Autores principales: Horibata, Yasuhiro, Ando, Hiromi, Satou, Motoyasu, Shimizu, Hiroaki, Mitsuhashi, Satomi, Shimizu, Yasuo, Itoh, Masahiko, Sugimoto, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562819/
https://www.ncbi.nlm.nih.gov/pubmed/28821867
http://dx.doi.org/10.1038/s41598-017-09205-1