An expandable embryonic stem cell-derived Purkinje neuron progenitor population that exhibits in vivo maturation in the adult mouse cerebellum

The directed differentiation of patient-derived induced pluripotent stem cells into cell-type specific neurons has inspired the development of therapeutic discovery for neurodegenerative diseases. Many forms of ataxia result from degeneration of cerebellar Purkinje cells, but thus far it has not bee...

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Detalles Bibliográficos
Autores principales: Higuera, Gustavo A., Iaffaldano, Grazia, Bedar, Meiwand, Shpak, Guy, Broersen, Robin, Munshi, Shashini T., Dupont, Catherine, Gribnau, Joost, de Vrij, Femke M. S., Kushner, Steven A., De Zeeuw, Chris I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562837/
https://www.ncbi.nlm.nih.gov/pubmed/28821816
http://dx.doi.org/10.1038/s41598-017-09348-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562837/
https://www.ncbi.nlm.nih.gov/pubmed/28821816
http://dx.doi.org/10.1038/s41598-017-09348-1

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