Aberrant low expression of p85α in stromal fibroblasts promotes breast cancer cell metastasis through exosome-mediated paracrine Wnt10b

P85α, which acts as a tumour suppressor, is frequently found to be downregulated in various human cancers. However, the role of p85α in the tumour microenvironment is unknown. Here, we report that aberrantly low expression of p85α in breast cancer stroma is clinically relevant to breast cancer disea...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Y, Zeng, C, Zhan, Y, Wang, H, Jiang, X, Li, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562851/
https://www.ncbi.nlm.nih.gov/pubmed/28394344
http://dx.doi.org/10.1038/onc.2017.100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562851/
https://www.ncbi.nlm.nih.gov/pubmed/28394344
http://dx.doi.org/10.1038/onc.2017.100

Ejemplares similares