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The inhibitory mechanism of Hal3 on the yeast Ppz1 phosphatase: A mutagenesis analysis
The Ser/Thr protein phosphatase (PPase) Ppz1 is an enzyme related to the ubiquitous type-1 PPases (PP1c) but found only in fungi. It is regulated by an inhibitory subunit, Hal3, which binds to its catalytic domain. Overexpression of Ppz1 is highly toxic for yeast cells, so its de-regulation has been...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562863/ https://www.ncbi.nlm.nih.gov/pubmed/28821821 http://dx.doi.org/10.1038/s41598-017-09360-5 |