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Dynamics of Hydration Water Plays a Key Role in Determining the Binding Thermodynamics of Protein Complexes
Interfacial waters are considered to play a crucial role in protein–protein interactions, but in what sense and why are they important? Here, using molecular dynamics simulations and statistical thermodynamic analyses, we demonstrate distinctive dynamic characteristics of the interfacial water and i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562873/ https://www.ncbi.nlm.nih.gov/pubmed/28821854 http://dx.doi.org/10.1038/s41598-017-09466-w |