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Reduction of the off-pathway iron-sulphur cluster N1a of Escherichia coli respiratory complex I restrains NAD(+) dissociation

Respiratory complex I couples the electron transfer from NADH to ubiquinone with the translocation of protons across the membrane. The reaction starts with NADH oxidation by a flavin cofactor followed by transferring the electrons through a chain of seven iron-sulphur clusters to quinone. An eighth...

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Detalles Bibliográficos
Autores principales: Gnandt, Emmanuel, Schimpf, Johannes, Harter, Caroline, Hoeser, Jo, Friedrich, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562879/
https://www.ncbi.nlm.nih.gov/pubmed/28821859
http://dx.doi.org/10.1038/s41598-017-09345-4