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Reduction of the off-pathway iron-sulphur cluster N1a of Escherichia coli respiratory complex I restrains NAD(+) dissociation
Respiratory complex I couples the electron transfer from NADH to ubiquinone with the translocation of protons across the membrane. The reaction starts with NADH oxidation by a flavin cofactor followed by transferring the electrons through a chain of seven iron-sulphur clusters to quinone. An eighth...
Autores principales: | Gnandt, Emmanuel, Schimpf, Johannes, Harter, Caroline, Hoeser, Jo, Friedrich, Thorsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562879/ https://www.ncbi.nlm.nih.gov/pubmed/28821859 http://dx.doi.org/10.1038/s41598-017-09345-4 |
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