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GADD45A plays a protective role against temozolomide treatment in glioblastoma cells

Glioblastoma multiforme (GBM) is one of the most aggressive cancers. Despite recent advances in multimodal therapies, high-grade glioma remains fatal. Temozolomide (TMZ) is an alkylating agent used worldwide for the clinical treatment of GBM; however, the innate and acquired resistance of GBM limits...

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Detalles Bibliográficos
Autores principales: Wang, Hsiao-Han, Chang, Tsuey-Yu, Lin, Wei-Chen, Wei, Kuo-Chen, Shin, Jyh-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562912/
https://www.ncbi.nlm.nih.gov/pubmed/28821714
http://dx.doi.org/10.1038/s41598-017-06851-3