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Cell line dependent expression of EpCAM influences the detection of circulating tumor cells with CellSearch

OBJECTIVES: The existence of circulating tumor cells has emerged as an important factor for prognosis and survival. The CellSearch method is the only circulating tumor cell detection method approved by the US Food and Drug Administration for clinical use. It relies on the detection of EpCAM (epithel...

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Detalles Bibliográficos
Autores principales: Lindgren, Gustaf, Wennerberg, Johan, Ekblad, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562942/
https://www.ncbi.nlm.nih.gov/pubmed/28894840
http://dx.doi.org/10.1002/lio2.83