Genetic deletion of mGlu2 metabotropic glutamate receptors improves the short-term outcome of cerebral transient focal ischemia

We have recently shown that pharmacological blockade of mGlu2 metabotropic glutamate receptors protects vulnerable neurons in the 4-vessel occlusion model of transient global ischemia, whereas receptor activation amplifies neuronal death. This raised the possibility that endogenous activation of mGl...

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Detalles Bibliográficos
Autores principales: Mastroiacovo, Federica, Moyanova, Slavianka, Cannella, Milena, Gaglione, Anderson, Verhaeghe, Remy, Bozza, Giovanna, Madonna, Michele, Motolese, Marta, Traficante, Anna, Riozzi, Barbara, Bruno, Valeria, Battaglia, Giuseppe, Lodge, David, Nicoletti, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562974/
https://www.ncbi.nlm.nih.gov/pubmed/28821279
http://dx.doi.org/10.1186/s13041-017-0319-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562974/
https://www.ncbi.nlm.nih.gov/pubmed/28821279
http://dx.doi.org/10.1186/s13041-017-0319-6

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