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PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis

BACKGROUND: The Mycobacterium tuberculosis (M.tb) protein kinase B (PknB) which is now proved to be essential for the growth and survival of M.tb, is a transmembrane protein with a potential to be a good drug target. However it is not known if this target remains conserved in otherwise resistant iso...

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Detalles Bibliográficos
Autores principales: Gupta, Anamika, Pal, Sudhir K., Pandey, Divya, Fakir, Najneen A., Rathod, Sunita, Sinha, Dhiraj, SivaKumar, S., Sinha, Pallavi, Periera, Mycal, Balgam, Shilpa, Sekar, Gomathi, UmaDevi, K. R., Anupurba, Shampa, Nema, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562987/
https://www.ncbi.nlm.nih.gov/pubmed/28821299
http://dx.doi.org/10.1186/s12941-017-0234-9