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PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis
BACKGROUND: The Mycobacterium tuberculosis (M.tb) protein kinase B (PknB) which is now proved to be essential for the growth and survival of M.tb, is a transmembrane protein with a potential to be a good drug target. However it is not known if this target remains conserved in otherwise resistant iso...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562987/ https://www.ncbi.nlm.nih.gov/pubmed/28821299 http://dx.doi.org/10.1186/s12941-017-0234-9 |