Age exacerbates microglial activation, oxidative stress, inflammatory and NOX2 gene expression, and delays functional recovery in a middle-aged rodent model of spinal cord injury

BACKGROUND: Spinal cord injury (SCI) among people over age 40 has been steadily increasing since the 1980s and is associated with worsened outcome than injuries in young people. Age-related increases in reactive oxygen species (ROS) are suggested to lead to chronic inflammation. The NADPH oxidase 2...

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Detalles Bibliográficos
Autores principales: von Leden, Ramona E., Khayrullina, Guzal, Moritz, Kasey E., Byrnes, Kimberly R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563003/
https://www.ncbi.nlm.nih.gov/pubmed/28821269
http://dx.doi.org/10.1186/s12974-017-0933-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563003/
https://www.ncbi.nlm.nih.gov/pubmed/28821269
http://dx.doi.org/10.1186/s12974-017-0933-3

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