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Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease

BACKGROUND: Efforts to identify fluid biomarkers of Parkinson’s disease (PD) have intensified in the last decade. As the role of inflammation in PD pathophysiology becomes increasingly recognized, investigators aim to define inflammatory signatures to help elucidate underlying mechanisms of disease...

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Detalles Bibliográficos
Autores principales: Eidson, Lori N., Kannarkat, George T., Barnum, Christopher J., Chang, Jianjun, Chung, Jaegwon, Caspell-Garcia, Chelsea, Taylor, Peggy, Mollenhauer, Brit, Schlossmacher, Michael G., Ereshefsky, Larry, Yen, Mark, Kopil, Catherine, Frasier, Mark, Marek, Kenneth, Hertzberg, Vicki S., Tansey, Malú G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563061/
https://www.ncbi.nlm.nih.gov/pubmed/28821274
http://dx.doi.org/10.1186/s12974-017-0935-1