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Evaluation of the impact of Illumina error correction tools on de novo genome assembly

BACKGROUND: Recently, many standalone applications have been proposed to correct sequencing errors in Illumina data. The key idea is that downstream analysis tools such as de novo genome assemblers benefit from a reduced error rate in the input data. Surprisingly, a systematic validation of this ass...

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Detalles Bibliográficos
Autores principales: Heydari, Mahdi, Miclotte, Giles, Demeester, Piet, Van de Peer, Yves, Fostier, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563063/
https://www.ncbi.nlm.nih.gov/pubmed/28821237
http://dx.doi.org/10.1186/s12859-017-1784-8