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aPKC Cycles between Functionally Distinct PAR Protein Assemblies to Drive Cell Polarity
The conserved polarity effector proteins PAR-3, PAR-6, CDC-42, and atypical protein kinase C (aPKC) form a core unit of the PAR protein network, which plays a central role in polarizing a broad range of animal cell types. To functionally polarize cells, these proteins must activate aPKC within a spa...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563072/ https://www.ncbi.nlm.nih.gov/pubmed/28781174 http://dx.doi.org/10.1016/j.devcel.2017.07.007 |