Cargando…

RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo

Nascent proteins can be positioned rapidly at precise subcellular locations by local protein synthesis (LPS) to facilitate localized growth responses. Axon arbor architecture, a major determinant of synaptic connectivity, is shaped by localized growth responses, but it is unknown whether LPS influen...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Hovy Ho-Wai, Lin, Julie Qiaojin, Ströhl, Florian, Roque, Cláudio Gouveia, Cioni, Jean-Michel, Cagnetta, Roberta, Turner-Bridger, Benita, Laine, Romain F., Harris, William A., Kaminski, Clemens F., Holt, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563073/
https://www.ncbi.nlm.nih.gov/pubmed/28781168
http://dx.doi.org/10.1016/j.neuron.2017.07.016