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RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo
Nascent proteins can be positioned rapidly at precise subcellular locations by local protein synthesis (LPS) to facilitate localized growth responses. Axon arbor architecture, a major determinant of synaptic connectivity, is shaped by localized growth responses, but it is unknown whether LPS influen...
Autores principales: | Wong, Hovy Ho-Wai, Lin, Julie Qiaojin, Ströhl, Florian, Roque, Cláudio Gouveia, Cioni, Jean-Michel, Cagnetta, Roberta, Turner-Bridger, Benita, Laine, Romain F., Harris, William A., Kaminski, Clemens F., Holt, Christine E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563073/ https://www.ncbi.nlm.nih.gov/pubmed/28781168 http://dx.doi.org/10.1016/j.neuron.2017.07.016 |
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