Amine Landscaping to Maximize Protein-Dye Fluorescence and Ultrastable Protein-Ligand Interaction

Chemical modification of proteins provides great opportunities to control and visualize living systems. The most common way to modify proteins is reaction of their abundant amines with N-hydroxysuccinimide (NHS) esters. Here we explore the impact of amine number and positioning on protein-conjugate...

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Detalles Bibliográficos
Autores principales: Jacobsen, Michael T., Fairhead, Michael, Fogelstrand, Per, Howarth, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563079/
https://www.ncbi.nlm.nih.gov/pubmed/28757182
http://dx.doi.org/10.1016/j.chembiol.2017.06.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563079/
https://www.ncbi.nlm.nih.gov/pubmed/28757182
http://dx.doi.org/10.1016/j.chembiol.2017.06.015

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