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Therapeutic Antibodies against Intracellular Tumor Antigens

Monoclonal antibodies are among the most clinically effective drugs used to treat cancer. However, their target repertoire is limited as there are relatively few tumor-specific or tumor-associated cell surface or soluble antigens. Intracellular molecules represent nearly half of the human proteome a...

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Detalles Bibliográficos
Autores principales: Trenevska, Iva, Li, Demin, Banham, Alison H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563323/
https://www.ncbi.nlm.nih.gov/pubmed/28868054
http://dx.doi.org/10.3389/fimmu.2017.01001