Remarkable Pharmacokinetics of Monoclonal Antibodies: A Quest for an Explanation

Monoclonal antibodies (MAbs) usually display slow and limited distribution with combined linear and non-linear elimination mechanisms. While studying individual pharmacokinetic profiles, it was noticed that MAb plasma concentration can vary abruptly over time, with one or more increases after the ti...

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Detalles Bibliográficos
Autores principales: Reijers, Joannes A. A., Moerland, Matthijs, Burggraaf, Jacobus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563346/
https://www.ncbi.nlm.nih.gov/pubmed/28000101
http://dx.doi.org/10.1007/s40262-016-0497-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563346/
https://www.ncbi.nlm.nih.gov/pubmed/28000101
http://dx.doi.org/10.1007/s40262-016-0497-x

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