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In Premature Newborns Intraventricular Hemorrhage Causes Cerebral Vasospasm and Associated Neurodisability via Heme-Induced Inflammasome-Mediated Interleukin-1 Production and Nitric Oxide Depletion

BACKGROUND: Intraventricular hemorrhage (IVH) occurs in 60–70% of neonates weighing 500–750 g and 10–20% of those weighing 1,000–1,500 g. All forms of IVH have been associated with neurocognitive deficits. Both subarachnoid and IVHs have been associated with delayed vasospasm leading to neurological...

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Detalles Bibliográficos
Autores principales: Eisenhut, Michael, Choudhury, Samyami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563367/
https://www.ncbi.nlm.nih.gov/pubmed/28868047
http://dx.doi.org/10.3389/fneur.2017.00423