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Stress-Activated Degradation of Sphingolipids Regulates Mitochondrial Function and Cell Death in Yeast

Sphingolipids are regulators of mitochondria-mediated cell death in higher eukaryotes. Here, we investigate how changes in sphingolipid metabolism and downstream intermediates of sphingosine impinge on mitochondrial function. We found in yeast that within the sphingolipid degradation pathway, the pr...

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Detalles Bibliográficos
Autores principales: Manzanares-Estreder, Sara, Pascual-Ahuir, Amparo, Proft, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563427/
https://www.ncbi.nlm.nih.gov/pubmed/28845213
http://dx.doi.org/10.1155/2017/2708345