Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development

Germline mutations of the SMARCB1 gene predispose to two distinct tumor syndromes: rhabdoid tumor predisposition syndrome, with malignant pediatric tumors mostly developing in brain and kidney, and familial schwannomatosis, with adulthood benign tumors involving cranial and peripheral nerves. The me...

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Detalles Bibliográficos
Autores principales: Vitte, Jeremie, Gao, Fuying, Coppola, Giovanni, Judkins, Alexander R., Giovannini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563506/
https://www.ncbi.nlm.nih.gov/pubmed/28824165
http://dx.doi.org/10.1038/s41467-017-00346-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563506/
https://www.ncbi.nlm.nih.gov/pubmed/28824165
http://dx.doi.org/10.1038/s41467-017-00346-5

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