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Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development
Germline mutations of the SMARCB1 gene predispose to two distinct tumor syndromes: rhabdoid tumor predisposition syndrome, with malignant pediatric tumors mostly developing in brain and kidney, and familial schwannomatosis, with adulthood benign tumors involving cranial and peripheral nerves. The me...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563506/ https://www.ncbi.nlm.nih.gov/pubmed/28824165 http://dx.doi.org/10.1038/s41467-017-00346-5 |