JunB promotes Th17 cell identity and restrains alternative CD4(+) T-cell programs during inflammation

T helper 17 (Th17) cell plasticity contributes to both immunity and autoimmunity; however, the factors that control lineage flexibility are mostly unknown. Here we show the activator protein-1 (AP-1) factor JunB is an essential regulator of Th17 cell identity. JunB activates expression of Th17 linea...

Descripción completa

Detalles Bibliográficos
Autores principales: Carr, Tiffany M., Wheaton, Joshua D., Houtz, Geoffrey M., Ciofani, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563507/
https://www.ncbi.nlm.nih.gov/pubmed/28824171
http://dx.doi.org/10.1038/s41467-017-00380-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563507/
https://www.ncbi.nlm.nih.gov/pubmed/28824171
http://dx.doi.org/10.1038/s41467-017-00380-3

Ejemplares similares