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JunB promotes Th17 cell identity and restrains alternative CD4(+) T-cell programs during inflammation
T helper 17 (Th17) cell plasticity contributes to both immunity and autoimmunity; however, the factors that control lineage flexibility are mostly unknown. Here we show the activator protein-1 (AP-1) factor JunB is an essential regulator of Th17 cell identity. JunB activates expression of Th17 linea...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563507/ https://www.ncbi.nlm.nih.gov/pubmed/28824171 http://dx.doi.org/10.1038/s41467-017-00380-3 |