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Single molecule high-throughput footprinting of small and large DNA ligands

Most DNA processes are governed by molecular interactions that take place in a sequence-specific manner. Determining the sequence selectivity of DNA ligands is still a challenge, particularly for small drugs where labeling or sequencing methods do not perform well. Here, we present a fast and accura...

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Detalles Bibliográficos
Autores principales: Manosas, Maria, Camunas-Soler, Joan, Croquette, Vincent, Ritort, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563512/
https://www.ncbi.nlm.nih.gov/pubmed/28824174
http://dx.doi.org/10.1038/s41467-017-00379-w