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Viral polymerase inhibitors T-705 and T-1105 are potential inhibitors of Zika virus replication

Since 2015, 69 countries and territories have reported evidence of vector-borne Zika virus (ZIKV) transmission. Currently, there are no effective licensed vaccines or drugs available for the treatment or prevention of ZIKV infection. We tested a series of compounds for their ability to inhibit ZIKV...

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Detalles Bibliográficos
Autores principales: Cai, Lei, Sun, Yajie, Song, Yabin, Xu, Likun, Bei, Zhuchun, Zhang, Dongna, Dou, Yuanyuan, Wang, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563514/
https://www.ncbi.nlm.nih.gov/pubmed/28597088
http://dx.doi.org/10.1007/s00705-017-3436-8